Clinical Research Directory
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2 clinical studies listed.
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Tundra lists 2 In-hospital Mortality clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT06651645
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
This study aims to perform a retrospective cohort study of administrative health data to understand how care delivery performance varies across US hospitals post-COVID-19 pandemic compared to the pre-pandemic performance. We also hope to identify which factors contribute to performance changes.
Gender: All
Ages: 18 Years - Any
Updated: 2025-04-29
1 state
NCT06648681
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium. Orexin is a neuromodulator thought to play an important role in disordered sleep, one of the instigators of delirium. Lembrorexant is an orexin antagonist, originally approved for sleep, that may also reduce the incidence of delirium. The Investigators propose a pilot study to determine the feasibility of a randomized controlled trial comparing Lembrorexant to placebo in patients following cardiac surgery in reducing the incidence of delirium, and improving sleep.
Gender: All
Ages: 61 Years - Any
Updated: 2025-04-23
1 state