Clinical Research Directory

A Multicomponent Physical Activity Intervention for Older Adults

ActiveKIT is a three-arm, parallel-group, individually randomized controlled trial. Community-dwelling adults aged 65 years or older (n=201) from Madrid and surrounding municipalities who were inactive were randomized into tree arms: a low-cost home-based exercise toolkit, the same toolkit plus remote specialist support, or usual-care. The intervention lasted 12 weeks, with assessments at baseline, 3 months, and 12 months.

Bridging the Gap: Implementing BRIDGES

Together with teenagers, we have developed a new approach: BRIDGES, which stands for "In Brussels, Resilience and Inclusion for Depression through Guidance, Exercise, and Support." BRIDGES aims to help young people with depression get moving again in their daily lives, at their own pace and in ways that are good for them.

Effects of Exercise Timing on Sleep Quality

Modern lifestyles are marked by a prevalence of sedentary behaviors and physical inactivity, which have been linked to numerous adverse health effects. While regular physical exercise is a well-established countermeasure, exercising in the late afternoon may paradoxically disrupt deep sleep due to increased core body temperature. Inactive and sedentary individuals, who often have impaired autonomic function compared to endurance-trained athletes, may be particularly susceptible to these negative effects, potentially resulting in compromised thermoregulation and exacerbated disruptions to deep sleep, a critical stage of sleep essential for overall recovery. Therefore, this study aims to investigate the impact of aerobic exercise performed in the late afternoon versus morning on: 1) deep sleep and sleep onset latency; and 2) core body temperature and its autonomic regulatory mechanisms on endurance-trained and inactive-sedentary people.

Differences in Autonomic Recovery Between Physically Active and Inactive Women Following an Automated Massage Chair Intervention

The goal of this study is to investigate whether an automated massage chair can improve the body's recovery system in healthy young women (aged 19-26 years) who are either physically active or inactive. The main questions it aims to answer are: 1. Does a single session in an automated massage chair improve heart rate variability (HRV) as an indicator of stress, relaxation, and recovery balance? 2. Do individuals who are more physically active recover better after using a massage chair compared to those who are inactive? Researchers will compare the physically active group to the physically inactive group to see if baseline physical activity levels influence the short-term recovery effects of the massage at different time points. Participants will: 1. Complete a standardized 20-minute automated massage chair session using a preset program at a self-selected moderate intensity. 2. Have their heart rate data collected at baseline, prior to the massage session. 3. Undergo follow-up heart rate data collection at 24, 48, and 72 hours after the session to monitor short-term recovery changes.