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Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

2 clinical studies listed.

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Infectious Complications

Tundra lists 2 Infectious Complications clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07043855

Duration of Perioperative Antibiotics in Pancreatoduodenectomy

The goal of this clinical trial is to learn if different prophylactic antibiotic regimens can prevent surgical site infections in adult patients undergoing pancreatoduodenectomy. The main questions it aims to answer are: Does a single preoperative dose of cefazolin reduce the risk of surgical site infection? Does a three-day combination of cefotaxime plus metronidazole reduce the risk of surgical site infection? Researchers will compare a single dose of cefazolin to a three-day course of cefotaxime + metronidazole to see if there is a difference in postoperative infection rates. Participants will: * Be randomly assigned to one of two antibiotic regimens before and after surgery * Receive either Arm A: one dose of cefazolin immediately before surgery Arm B: cefoxitin for perioperative antibiotics followed by cefotaxime plus metronidazole administered for three days after surgery * Undergo routine postoperative monitoring for signs of infection * Have any surgical site infections and related complications recorded until 30 days after surgery

Gender: All

Ages: 18 Years - 80 Years

Updated: 2025-07-02

Pancreatoduodenectomy
PPPD
Infectious Complications
RECRUITING

NCT06719596

Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD

Probiotics combined with enteral nutrition reduces postoperative infectious complications in PD

Gender: All

Ages: 18 Years - Any

Updated: 2024-12-06

1 state

Infectious Complications