Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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Inguinal Hernia Without Obstruction or Gangrene

Tundra lists 1 Inguinal Hernia Without Obstruction or Gangrene clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07604272

Reversing InGuinal Hernia Trial: The Evaluation of Sex Hormones to Reverse Inguinal Hernias in Males

This is a prospective, single-center, three-arm Phase 1 safety and feasibility trial evaluating anti-estrogen therapy in men age 50 years and older with symptomatic unilateral inguinal hernias. Participants will be randomized to receive fulvestrant 250 mg intramuscularly, fulvestrant 500 mg intramuscularly, or letrozole 5 mg orally for 6 months. The study will evaluate safety, tolerability, feasibility, hormone changes, hernia size, patient-reported outcomes, bone density, and imaging-based hernia classification.

Gender: MALE

Ages: 50 Years - Any

Updated: 2026-06-11

1 state

Inguinal Hernia Unilateral

Inguinal Hernia Bilateral

Inguinal Hernia Without Obstruction or Gangrene