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Inherited Retinal Dystrophy Primarily Involving Sensory Retina

Tundra lists 1 Inherited Retinal Dystrophy Primarily Involving Sensory Retina clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT05626920

Disulfiram for Treatment of Retinal Degeneration

Aberrant retinoic acid signaling driven by the degenerating outer retina leads to pathological changes to the inner retina. The resulting hyperactivity of retinal ganglion cells leads to further diminution of the remaining vision in those afflicted with inherited retinal diseases. Inhibition of this pathway has led to improved visual function in murine models of retinal degeneration. This can be accomplished in humans with the FDA-approved irreversible inhibitor of aldehyde dehydrogenases, disulfiram.

Gender: All

Ages: 18 Years - Any

Updated: 2024-12-06

1 state

Inherited Retinal Dystrophy Primarily Involving Sensory Retina