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Tundra lists 2 Intrapartum Fetal Distress clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07881744
Prediction of Intrapartum Fetal Compromise After Elective Induction of Labour
Each fetus has a different metabolic capacity at the onset of labor, and in cases of an imbalance between fetal demands and placental oxygen supply, fetal hypoxia occurs. In this scenario, and to avoid permanent fetal damage, a cesarean section (CS) for intrapartum fetal compromise (IFC) might be needed to minimize the potential consequences of sustained hypoxia.
Gender: FEMALE
Ages: 18 Years - 40 Years
Updated: 2026-10-19
NCT07846137
The Ophthalmic Artery Doppler Evaluation Prior to Labor Induction and Adverse Intrapartum Fetal Outcomes
The ophthalmic artery Doppler has been recently proposed as a potential "soft marker" for placental insufficiency in retrospective and observational studies, with similar clinical significance with respect to Uterine Artery (UA) Doppler evaluation and it is currently being investigated as an adjunctive clinical instrument to predict pre-eclampsia (PE) occurrence. Placental insufficiency strictly correlates with intrapartum fetal adverse outcomes and a concomitant induction of labor, alone, may further increase the hypoxic stress on the fetus during labor. This can be reflected by cardiotocographic alterations during labor, ultimately leading to emergency cesarean deliveries or instrumental vaginal deliveries. Despite great advancements in understanding various maternal-fetal pathologies, the investigators are still not able to properly detect fetuses that are at higher risk for intrapartum compromise among those receiving an induction of labor. Therefore, the aim of this prospective study is to investigate any potential association between altered ophthalmic artery Doppler PSV ratio measured before labor induction in at-term, pregnant patients with intra-partum fetal compromise. Furthermore, the investigators aim to also measure an additional parameter that is the optic nerve sheath diameter (ONSD) - an indirect measure of intracranial pressure - before and after the second stage of labour, with the aim of studying its physiology during and after delivery.
Gender: FEMALE
Ages: 18 Years - Any
Updated: 2026-09-29