Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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KRAS/NRAS Mutation

Tundra lists 1 KRAS/NRAS Mutation clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT06106308

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

The purpose of this study is to assess 2 different doses of onvansertib to select the lowest dose that is maximally effective, and to assess the safety, efficacy, pharmacokinetics, and pharmacodynamics of onvansertib in combination with FOLFIRI + bevacizumab or FOLFOX + bevacizumab in patients with KRAS or NRAS-mutated metastatic colorectal cancer (CRC) in the first-line setting.

Gender: All

Ages: 18 Years - Any

Updated: 2026-01-12

21 states

Metastatic Colorectal Cancer

CRC

KRAS/NRAS Mutation