NOT YET RECRUITING
NCT07831577
Efficacy and Safety of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
The goal of this clinical trial is to learn if GNSC-001 works to treat knee osteoarthritis in adults. It will also learn about the safety of GNSC-001. The main questions it aims to answer are:
1. Does GNSC-001 lower daily knee joint pain and improve function in participants?
2. What medical problems do participants have when taking GNSC-001?
Researchers will compare GNSC-001 to a placebo (a look-alike substance that contains no drug) to see if GNSC-001 works to treat knee osteoarthritis.
Participants will:
1. Receive a single injection of immune-modulation, and GNSC-001 or a placebo, in their knee
2. Take an oral immune-modulating pill every day for the first 22 days
3. Visit the clinic at least 9 times over 2 years for checkups and tests
4. Keep a diary of their symptoms and the number of times they use a rescue medication
Gender: All
Ages: 40 Years - 80 Years
Knee Arthritis Osteoarthritis
Knee Arthritis, Osteoarthritis
Knee Arthritis
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