Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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Leptomeningeal Neoplasm

Tundra lists 3 Leptomeningeal Neoplasm clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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RECRUITING

NCT03025256

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

This phase I/Ib trial studies the side effects and best dose of intrathecal nivolumab, and how well it works in combination with intravenous nivolumab in treating patients with leptomeningeal disease. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Gender: All

Ages: 18 Years - Any

Updated: 2026-04-02

1 state

Acral Lentiginous Melanoma
Central Nervous System Melanoma
Clinical Stage IV Cutaneous Melanoma AJCC v8
+7
RECRUITING

NCT04988009

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

This study evaluates patient perceptions around quality of care through telemedicine in neuro-oncology. Studying questionnaires related to perceptions quality of care through telemedicine in patients with brain cancer may help doctors to improve the delivery of care through this modality.

Gender: All

Ages: 18 Years - Any

Updated: 2026-03-05

1 state

Central Nervous System Neoplasm
Leptomeningeal Neoplasm
Metastatic Malignant Neoplasm in the Brain
+1
ACTIVE NOT RECRUITING

NCT04250545

Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer

This phase I/Ib trial studies the side effects and best dose of CB-839 HCl when given together with sapanisertib in treating patients with non-small cell lung cancer that has spread to other places in the body (advanced). CB-839 HCl and sapanisertib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Gender: All

Ages: 18 Years - Any

Updated: 2025-11-25

2 states

Leptomeningeal Neoplasm
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Brain
+4