Clinical Research Directory

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1 clinical study listed.

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Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))

Tundra lists 1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07430202

A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipilimumab in Patients With Advanced Stage Fibrolamellar Carcinoma (FLC)

The purpose of this study is to determine whether the combination of a neoantigen vaccine targeting the DNAJB1-PRKACA fusion kinase in combination with DRP-104, Nivolumab and Ipilimumab is safe and yields a clinically compelling antitumor activity measured as based on objective response rate (ORR, assessed by RECIST 1.1). Secondary objectives include progression-free survival (PFS) and overall survival (OS).

Gender: All

Ages: 12 Years - Any

Updated: 2026-02-24

1 state

Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))