NOT YET RECRUITING
NCT07753148
Safety and Tolerability of REGN17235 in Adult Participants With Clonal Cytopenia of Undetermined Significance and Low-Risk Myelodysplastic Syndrome With SF3B1 Mutation
This study will test a study drug called REGN17235 (the "study drug") to see if it can help treat Clonal Cytopenia of Undetermined Significance (CCUS) and Low-Risk Myelodysplastic Syndrome (LR-MDS) with a specific genetic mutation (SF3B1 Mutation).
The study is looking at:
* What side effects the study drug might cause
* How well the study drug works
* How much of the study drug is in the blood at different times
* If the body makes antibodies (proteins that attach to substances your body does not recognize) against the study drug; this may cause the study drug to not work as well.
* What is the best dose of the study drug to treat CCUS and LR-MDS
Gender: All
Ages: 18 Years - Any
Clonal Cytopenia of Undetermined Significance (CCUS)
Low-Risk Myelodysplastic Syndrome (LR-MDS)