Clinical Research Directory

Comparison of Three Surgical Approaches for Lateral Sinus Floor Elevation

This study compares three surgical approaches used during lateral sinus floor elevation, a procedure performed to increase bone height in the back part of the upper jaw before or together with dental implant placement. Participants are randomly assigned to one of three groups: a standard surgical procedure, a technique using an epinephrine-soaked cotton roll to help control bleeding, or a piezoelectric surgical technique. The study compares these approaches in terms of bleeding during surgery, visibility of the surgical field, ease of performing the procedure, operation time, and Schneiderian membrane perforation, an intraoperative complication that can occur during sinus lift surgery. Patient-related and anatomical factors, including age, sex, smoking status, residual bone height, sinus membrane thickness, lateral sinus wall thickness, and the presence of sinus septa, are also recorded. The aim is to determine whether the surgical approach influences intraoperative conditions and membrane perforation and whether patient-related or anatomical factors are associated with these outcomes.

Radiographical, Histomorphometrical and Biomarker Analysis After Maxillary Sinus Augmentation Utilizing Xenograft Particulate Bone Graft Mixed With Parathyroid Hormone

This study aimed the to investigate the beneficial effect of combining PTH with bovine-derived bone graft bone in maxillary sinus augmentation. There is limited information available about the effect of PTH on maxillary sinus augmentation to achieve a clear understanding of PTH's efficacy in bone regeneration and bone remodelling through radiological, clinical, biomarker, histological and histomorphometric assessment . Objectives 1. Evaluation of the bone density at the planned implants sites using cone beam computed tomography (CBCT). 2. Histomorphometry examination of maxillary sinus bone to measure (bone trabeculae, connective tissue, osteoblast, osteocyte) after healing 4 months after augmentation. 3. Osteopontin as biomarker analysis for bone regeneration and osteoblast activity. 4. Evaluate the primary stability of implant in upper posterior area filled with PTH (1 34) and bovine-derived bone graft compared to bovine-derived bone graft alone.