Clinical Research Directory

Can Cranberry Juice Enhance the Cognition Accuracy and Alleviate Negative Mental Consequences During Multitasking?

This clinical trial aims to investigate the effects of a 70-day consumption of cranberry juice on cognitive and motor accuracy, mental and physiological stress, and stress response in healthy men and women between the ages of 30 and 55 who engage in multitasking. The trial will utilize a randomized, double-blinded, placebo-controlled design. It is worth noting that studies have shown that over half of middle-aged Americans experience stress, which can lead to cognitive decline and depression. Previous clinical trials have indicated that consuming polyphenol-rich foods can have positive effects on cognitive function in humans. However, no study to date has examined the long-term effects of cranberry juice consumption on cognitive performance, mental stress, and stress response specifically in individuals engaged in multitasking. Based on this gap in knowledge, the investigators hypothesize the following: (1) chronic consumption of cranberry juice will improve cognitive and motor accuracy, as well as mental and psychological stress responses in young adults subjected to intense multitasking. (2) cranberry juice consumption will alleviate the negative consequences of frequent intense multitasking, such as fatigue, mood fluctuations, cognitive impairment, and memory issues. Additionally, it is expected to have a positive impact on stress biomarkers and neurotransmitter levels. By conducting this clinical trial, the investigators aim to shed light on the potential benefits of cranberry juice consumption in improving cognitive performance, mitigating mental stress, and positively influencing stress responses in individuals who engage in intense multitasking.

MultiCPR: The Influence of Resuscitation on History Recall

In this randomized crossover trial, participants begin with chest compressions at a 30:2 ratio while a study team member provides ventilation. In Scenario A, participants perform two-person CPR and receive a prerecorded patient history after 30 seconds. In Scenario B, participants only listen to the patient's history without performing CPR or any concurrent task. To control for time-dependent memory decay, Scenario B includes a 3-minute delay before completing the questionnaire, matching the interval between information exposure and recall in Scenario A. After each scenario, participants complete the NASA-TLX workload assessment and a semi-open questionnaire on the patient's history. A modified Brown-Peterson task follows as a washout period: participants subtract 3 repeatedly from 309 for 1 minute, followed by 4 minutes of rest without phone use or conversation. Calculation performance is not analyzed.