Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis

Tundra lists 1 Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT03862157

Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

This phase I/II trial studies the best dose of venetoclax when given together with azacitidine and pevonedistat and to see how well it works in treating patients with newly diagnosed acute myeloid leukemia. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Venetoclax may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Pevonedistat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving azacitidine, venetoclax, and pevonedistat may work better in treating patients with acute myeloid leukemia.

Gender: All

Ages: 18 Years - Any

Updated: 2026-03-11

1 state

Acute Myeloid Leukemia

Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative

Chronic Eosinophilic Leukemia, Not Otherwise Specified

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