Clinical Research Directory

Effect of Moringa Oleifera, Zingiber Officinale, and Curcuma Xanthorrhiza Extracts for Nausea and Vomiting in First-Trimester Pregnancy

This retrospective cohort study will evaluate the association between adjunctive Moringa oleifera, Zingiber officinale, and Curcuma xanthorrhiza extracts and changes in Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scores among patients with nausea and vomiting of pregnancy during the first trimester. Eligible medical records will be classified into two groups according to the treatment previously received as part of routine clinical care. The adjunctive group received ondansetron together with a fixed-dose herbal extract combination, whereas the control group received ondansetron without the herbal combination. The primary outcome will be the change in PUQE score from baseline to day 3. The study will also compare the proportion of patients achieving a clinically relevant reduction in PUQE score between the two groups.

Guided Imagery for Nausea and Well-Being in Pregnant Women

This study aims to evaluate the effect of a guided imagery-based psychoeducational intervention on nausea and vomiting severity and psychological well-being in pregnant women. The intervention includes structured psychoeducation and guided imagery sessions designed to promote relaxation, enhance symptom management, and improve overall well-being. Pregnant women in the first trimester experiencing nausea and vomiting were randomly assigned to either the intervention group or the control group. The intervention group received a four-session guided imagery-based psychoeducation program supported by home-based audio practice, while the control group received routine antenatal care. Outcomes were assessed before and after the intervention using standardized measurement tools.