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Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

5 clinical studies listed.

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Non Small Cell Lung Cancer Stage III

Tundra lists 5 Non Small Cell Lung Cancer Stage III clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT05382052

Study of ctDNA as Prognostic Factor on Resectable Stage IIIA NSCLC Patients Treated With Neoadjuvant Treatment

This is an observational, prospective, multicentre and nationwide study. The study enroll resectable stage IIIA non-small cell lung cancer patients that are going to receive neoadjuvant treatment in real world. The primary objective of this study is evaluating whether there is a significant association between ctDNA clearance (no detection of ctDNA) after neoadjuvant treatment and before surgery and progression free survival.

Gender: All

Ages: 18 Years - Any

Updated: 2025-11-19

14 states

Non Small Cell Lung Cancer Stage III
Neoadjuvant Treatment
ACTIVE NOT RECRUITING

NCT04711330

Response and Toxicity Prediction by Microbiome Analysis After (Concurrent) Chemoradiotherapy

The predictive value of the microbiome (throat swabs, stool and of bronchial samples) to identify patients who will relapse during durvalumab treatment after CRT (False negative Rate) at 6 months. Exploratory endpoints include the effects of antibiotic therapy before and during IO treatment on toxicity and response rate. The role of exhaled breath analysis in prediction of response and toxicity will also be investigated.

Gender: All

Ages: 18 Years - Any

Updated: 2025-10-06

1 state

Non Small Cell Lung Cancer Stage III
Immunotherapy
RECRUITING

NCT02622581

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients

Open, non-interventional, prospective, multi-center clinical research platform with the main objective to assess molecular biomarker testing, treatment and outcome of patients with NSCLC or SCLC in Germany

Gender: All

Ages: 18 Years - Any

Updated: 2025-02-18

Metastatic Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer Metastatic
Non-small Cell Lung Cancer Stage II
+3
ACTIVE NOT RECRUITING

NCT04392505

Durvalumab(MEDI4736) After chemoRadioTherapy(DART) for NSCLC-a Translational and Biomarker Study

The main aim is to identify and describe biomarkers in different sample types related to chemoradiation followed by durvalumab treatment for stage III PD-L1 negative and positive non-small cell lung cancer (NSCLC) patients' eligible for curatively intended chemoradiation. The hypothesis is that clinical differences in course of disease reflect underlying biological characteristics.

Gender: All

Ages: 18 Years - Any

Updated: 2024-02-29

Cancer
Non Small Cell Lung Cancer
Non Small Cell Lung Cancer Stage III
+2
NOT YET RECRUITING

NCT04465968

Efficacy and Safety of CRT, Durvalumab and Surgery for SST

The safety and efficacy of multimodality treatment of pre- and post-operative durvalumab therapy after pre-operative chemoradiotherapy for resectable superior sulcus tumor (SST) and durvalumab maintenance therapy after chemoradiotherapy for unresectable SST

Gender: All

Ages: 20 Years - 75 Years

Updated: 2020-07-10

Superior Sulcus Tumor
Non-small Cell Lung Cancer Stage IIB
Non Small Cell Lung Cancer Stage III