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Clinical Research Directory

Browse clinical research sites, groups, and studies.

2 clinical studies listed.

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Non-Carious Cervical Lesions (NCCLs)

Tundra lists 2 Non-Carious Cervical Lesions (NCCLs) clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07734935

The Effect of Retraction Cord on the Surrounding Periodontal Tissues in Restorative Treatment

The goal of this clinical trial is to learn whether a retraction cord affects gum health when used during tooth restoration procedures. A retraction cord is a thin thread that dentists sometimes place between the tooth and the gum surrounding it, to gently push the gum aside so the restoration can be performed in a clean surface isolated from saliva. The study includes adult teeth with tooth damage near the gumline that has not been caused by decay, yet needs a restoration. The main research question is: Does using a retraction cord make a difference for gum health as opposed to not using one? Participants will be assigned into four separate groups. Two groups will receive a restoration with one type of bonding material, either with or without a retraction cord. The other two groups will receive a restoration with a different kind of bonding material, either with or without a retraction cord. Researchers will check gum health status before the restorations and again on days 1, 7, and 28. They will observe symptoms such as swelling in the gums, bleeding of the gums, and gum margin positions. A fluid sample from the area between the gum and tooth will be collected to test for molecules of inflammation.

Gender: All

Ages: 18 Years - Any

Updated: 2026-08-04

Tooth Abrasion
Gingival Recessions
Non-Carious Cervical Lesions (NCCLs)
+3
RECRUITING

NCT07687654

Root Coverage Performance of Restorative Materials in Class V Cavities

This prospective randomized controlled clinical trial aims to evaluate the influence of different restorative materials placed in Class V cervical lesions on the clinical outcomes of root coverage surgery using a subepithelial connective tissue graft. Patients with Cairo RT1 (Miller Class I-II equivalent) gingival recession associated with non-carious cervical lesions or existing cervical restorations will receive one of the restorative approaches according to the study protocol. Clinical parameters, including the percentage of root coverage and soft tissue stability, will be evaluated during follow-up to determine which restorative approach provides the most favorable clinical outcome.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-07-07

1 state

Gingival Recession
Non-Carious Cervical Lesions (NCCLs)