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Clinical Research Directory

Browse clinical research sites, groups, and studies.

4 clinical studies listed.

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PNH - Paroxysmal Nocturnal Hemoglobinuria

Tundra lists 4 PNH - Paroxysmal Nocturnal Hemoglobinuria clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT07212426

Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in PNH Patients.

This is a multicenter, randomized, open-label, Phase II clinical study to evaluate the efficacy, safety, and pharmacokinetics of LP-005 injection in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).

Gender: All

Ages: 18 Years - 65 Years

Updated: 2026-01-16

PNH - Paroxysmal Nocturnal Hemoglobinuria
RECRUITING

NCT07256301

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

This is a multicenter, open-label, Phase Ib clinical trial designed to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple doses of the humanized monoclonal antibody EA5 in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).

Gender: All

Ages: 18 Years - Any

Updated: 2025-12-01

2 states

PNH - Paroxysmal Nocturnal Hemoglobinuria
RECRUITING

NCT06978699

A Phase II Study Evaluating the Efficacy and Safety of XH-S003 Capsules in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

This is a multicenter, randomized, single-blind Phase II trial to evaluate the efficacy and safety of XH-S003 capsules in PNH patients. About 24 PNH patients will be enrolled and randomized to three dose levels and take XH-S003 capsules orally

Gender: All

Ages: 18 Years - Any

Updated: 2025-05-18

PNH - Paroxysmal Nocturnal Hemoglobinuria
NOT YET RECRUITING

NCT05731050

Study of NM8074 in Soliris-Treated Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

The proposed study, NM8074-PNH-101, is a phase II, open-label, multi-dose, unicenter trial to evaluate the safety and efficacy of NM8074 in Soliris-treated PNH subjects.

Gender: All

Ages: 18 Years - 65 Years

Updated: 2025-03-30

PNH - Paroxysmal Nocturnal Hemoglobinuria