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Part1: Advanced B-cell Malignancies

Tundra lists 1 Part1: Advanced B-cell Malignancies clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NCT03198650

A Phase 1 Study of Acalabrutinib in Japanese Adult Patients With Advanced B-cell Malignancies

This is a multicenter, open-label Phase 1 study of acalabrutinib, a selective and irreversible Bruton's tyrosine kinase inhibitor, in Japanese adult patients with advanced B-cell malignancies. This study is divided into 3 parts: Part 1 (dose-confirmation phase), Part 2 (dose-expansion phase) and Part 3 (dose-confirmation phase for combination therapy).

Gender: All

Ages: 20 Years - 120 Years

Updated: 2025-10-09

Part1: Advanced B-cell Malignancies

Part2: r/rCLL and r/rMCL

Part3: Untreated CLL