Clinical Research Directory
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Tundra lists 2 Periventricular White Matter Abnormalities clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.
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NCT07688746
Neonatal White Matter Injury Trial (WRAP)
The researchers are investigating a new treatment for white matter injury, which is a common type of brain injury in premature babies. The drug, clemastine, is experimental. This means that the drug is not approved by the Food and Drug Administration (FDA) for the treatment of white matter injury. The main purpose of this study is to learn whether clemastine is safe to give to infants with white matter injury. The researchers also want to understand how much clemastine gets into an infant's body when the medication is taken by mouth, and how long it stays in the body.
Gender: All
Ages: 3 Weeks - 20 Weeks
Updated: 2026-07-28
1 state
NCT06575283
Predicting Cerebral Palsy in Infants With White Matter Injury Using MRI
The goal of this study is to determin the MRI features associated with cerebral palsy and to develop prediction models of pediatric disorders by combining MRI with artificial intelligence. The main questions it aims to answer are: * How to achieve features on conventional MRI associated with cerebral palsy? * How to predict the risk of cerebral palsy in infants aged 6 to 2 years based on conventional MRI and deep learning? Researchers will compare characteristics of periventricular white matter injury with cerebral palsy to those without cerebral palsy. Participants will be asked to provide MRI data, clinical diagnoses information, and follow-up outcomes.
Gender: All
Ages: 6 Months - 2 Years
Updated: 2024-09-19
1 state