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Pineocytoma

Tundra lists 1 Pineocytoma clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT06357377

A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors

This is an open label, Phase 1b safety, dose-finding, brain tumor delivery, and pharmacokinetics study of intranasal NEO100 in patients with pediatric-type diffuse high grade gliomas. Patients will receive IN NEO100 that will follow a dose titration design, followed by a standard dose escalation design to establish safety. Brain tumor delivery of NEO100 will be confirmed in each disease sub-type by surgical resection/needle biopsy only if clinically indicated and scheduled for clinical purposes and testing with residual tissue for NEO100 and the major metabolite of NEO100 (Perillic Acid).

Gender: All

Ages: 5 Years - 18 Years

Updated: 2026-01-14

Pediatric Tumor of CNS

Pediatric Tumor of Brain

Diffuse Midline Glioma, H3 K27M-Mutant