Clinical Research Directory

Effect of Health Belief Model-Based Peer Education on Premenstrual Syndrome

This study aims to examine the effect of peer education based on the Health Belief Model (HBM) on university students' coping skills with premenstrual syndrome (PMS). PMS is a common health problem that lowers women's quality of life and negatively affects their social and academic performance. The study will be conducted with 56 female students studying at Istanbul Atlas University, utilizing a randomized controlled design. Following the administration of a pre-test, participants diagnosed with PMS will be randomly assigned to either the intervention or control groups. The intervention group will be taught strategies for coping with PMS symptoms through peer education, while the control group will only receive an educational brochure. The training sessions will be structured framework of the Health Belief Model and will cover topics such as the definition, causes, and risk factors of PMS, as well as healthy lifestyle habits (nutrition, exercise, stress management). Data will be collected using pre-test and post-test methods, and changes in PMS symptoms will be analyzed using SPSS software. The study is expected to increase students' awareness of PMS and strengthen their ability to cope with symptoms as a result of peer education. The study duration is planned for 12 months and is projected to be conducted between 2025 and 2026. The intervention group will receive peer education based on the Health Belief Model framework covering topics such as the causes, symptoms, and risk factors of PMS. The training will be delivered in a classroom setting as two sessions conducted biweekly. Lecture, group discussions, and audiovisual materials will be used as educational methods. Personal Information Form and the Premenstrual Syndrome Scale will be used as data collection tools. The scale will be first administered in the pre-test to evaluate the severity of the participants' PMS symptoms. Following random assignment, the scale will be administered three times prior to three menstrual cycles for both intervention and control groups. The obtained data will be analyzed using SPSS software, and differences between groups will be evaluated using independent samples t-test and analysis of variance (ANOVA). The statistical significance level will be accepted as p\<0.05. The findings to be obtained from this study are expected to demonstrate the potential of the peer education method to increase PMS awareness and strengthen coping skills with symptoms. The results of the research aim to contribute to the development of health education programs targeted toward university students.

Mandala and Music for PMS Relief

Purpose: The aim of this project is to examine the effects of mandala painting and music performance interventions on premenstrual syndrome symptoms and quality of life. The hypotheses of the study are as follows: Coloring mandalas has a positive effect on premenstrual syndrome symptoms. Listening to music has a positive effect on premenstrual syndrome symptoms. Listening to music has a positive effect on quality of life. Coloring mandalas has a positive effect on quality of life.

Efficacy of a Food Supplement in Relieving Premenstrual Syndrome Symptoms

The aim of this clinical trial, funded by Activ'Inside, is to evaluate the efficacy of a food supplement in relieving Premenstrual Syndrome (PMS) Symptoms. The study will be performed on 110 healthy women who experience mild/moderate Premenstrual Syndrome (PMS) symptoms, under the supervision of a board-certified Gynecologist. Half of the subjects will assume the active product and half of the subjects will assume a placebo (a product without active ingredients). Specific assessments will be carried out before and after 1, 2 and 3 menstrual cycles of product intake. Also, the possible occurrence of adverse events will be recorded.

Identification and Validation of Epigenetic Biomarkers of PMDD

This research is being done to examine epigenetic markers and mood changes across the menstrual cycle, particularly in premenstrual dysphoric disorder (PMDD). The investigators previously identified epigenetic biomarkers of postpartum depression, another reproductive affective disorder, and in this study aim to determine if these biomarkers also distinguish PMDD cases from healthy controls at different points in the menstrual cycle. By collecting biological samples (such as blood) and monitoring mood changes across the menstrual cycle, the investigators will be able to determine whether these epigenetic markers are associated with PMDD. The investigators plan to study these epigenetic markers during the follicular phase (roughly the first half of the menstrual cycle, from menses until ovulation) and the luteal phase (roughly the second half of the menstrual cycle, from ovulation to menses). The investigators will study this in two groups: 1) individuals who do NOT have premenstrual mood symptoms, and 2) individuals with premenstrual syndrome/premenstrual dysphoric disorder (PMS/PMDD). The results will provide a comprehensive view of the changes in these systems across the menstrual cycle. This will add to the investigators understanding of the mechanisms that may cause PMS/PMDD.

Efficacy of Nutrition Education in Alleviating Premenstrual Syndrome (PMS) Among Chinese College Students at Hainan University, China

This study aims to evaluate the efficacy of nutrition education-based intervention on PMS severity, perceived stress, and lifestyle-related outcomes among the students at Hainan Vocational University of Science and Technology

Effects of Yoga on Balance, Cognition, Posture, and Body Awareness in Premenstrual Syndrome (PMS)

Premenstrual syndrome (PMS) is characterized by a combination of cognitive, somatic, behavioral, and emotional disorders that occur during the late luteal phase of the menstrual cycle, resolve rapidly after menstruation, and can be severe enough to disrupt daily activities. When reviewing the literature, studies examining the effects of yoga-based exercises on premenstrual syndrome appear to be quite limited. Our aim is to raise awareness among professionals working in this field in our country, contributing to the reduction of symptoms and improvement of the quality of life of individuals with premenstrual syndrome.