Clinical Research Directory

Prognostic Nutritional Index and Postoperative Complications in Oncologic Surgery

Malnutrition, anorexia, and cachexia are common in patients undergoing oncologic surgery and can negatively affect treatment outcomes. The Prognostic Nutritional Index (PNI), calculated from serum albumin levels and total lymphocyte count, is a simple and reliable marker of nutritional and immune status. Although PNI has been studied in various malignancies, its predictive value for postoperative outcomes across all oncologic surgical procedures has not been fully evaluated. This study aims to assess the role of PNI in predicting postoperative outcomes and prognosis in patients undergoing different types of oncologic surgery.

Immune-Inflammatory Markers in Aortic Dissection

Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for assessing risk, this knowledge could in the future help physicians follow their patients more effectively. The aim of this study is to investigate this possibility scientifically. It is based on the evaluation of information obtained from blood tests that are already being performed. Its purpose is to generate general knowledge that may contribute to the care of future patients. The study itself does not change decisions about your treatment; all decisions regarding your treatment and follow-up rest with your doctor, who evaluates your condition in its entirety. It is designed to evaluate the relationship between preoperative/postoperative systemic immune-inflammatory and nutritional markers (SII, NLR, PLR, CAR, PNI) and indicators of mortality and morbidity (length of stay and changes in kidney function) in patients with acute aortic dissection. The goal is to investigate the potential of easily accessible laboratory parameters to contribute to risk stratification. The relationship between the markers and outcomes will be analyzed using appropriate statistical methods. This study is based on the evaluation of information in patients' existing medical records and blood tests. The data are processed in accordance with the relevant ethical rules and privacy principles, with patient identity kept confidential. Taking part in the study does not require any additional procedure, additional blood draw, or change in treatment.