Clinical Research Directory

Browse clinical research sites, groups, and studies.

1 clinical study listed.

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Programmed Cell Death-1 (PD1, PD-1)

Tundra lists 1 Programmed Cell Death-1 (PD1, PD-1) clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT06049212

Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)

This is a phase 1 trial of the safety, tolerability, and pharmacokinetics (PK) of sacituzumab tirumotecan monotherapy, and of sacituzumab tirumotecan in combination with pembrolizumab (MK-3475) or pembrolizumab + carboplatin, in Japanese participants with advanced solid tumors or treatment-naïve advanced or metastatic non-small cell lung cancer (NSCLC). Per protocol amendment 04, Arm 3: Pembrolizumab/Carboplatin + sacituzumab tirumotecan Combination Therapy was discontinued, and subsequently all Arm 3 procedures, recruitment, and descriptions were removed.

Gender: All

Ages: 18 Years - Any

Updated: 2025-12-19

7 states

Non-small Cell Lung Cancer

Solid Tumors

Programmed Cell Death-1 (PD1, PD-1)