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Clinical Research Directory

Browse clinical research sites, groups, and studies.

5 clinical studies listed.

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Proximal Caries

Tundra lists 5 Proximal Caries clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07550179

Labial White Spot Lesions and Proximal Caries Development in Orthodontic Patients Using Clear Aligners Versus Traditional Braces.

This randomized clinical trial evaluates the risk of developing early tooth decay in patients undergoing orthodontic treatment with either traditional fixed braces or clear aligners. Because orthodontic appliances can trap plaque and make tooth cleaning difficult, patients are at a higher risk for developing early decay, such as chalky "white spot lesions" on the visible surfaces of the teeth and hidden decay between the teeth (proximal caries). In this six-month study, 24 participants are randomly assigned to receive either fixed braces or clear aligners. Researchers will monitor the participants' oral health prior to treatment, at 3 months, and at 6 months. To safely and accurately detect decay, the study uses standard visual examinations for the front of the teeth and a radiation-free optical scanner (Near-Infrared Imaging, or NIRI) to detect hidden cavities between the teeth. The primary goal of this study is to compare how many new white spot lesions and hidden cavities between teeth develop in each group over the six-month observation period. Additionally, the study tracks how these early lesions behave over time, monitors changes in the patients' daily oral hygiene, and records how often patients in each group require professional dental cleaning procedures. Ultimately, this study aims to help patients and dental professionals make better-informed decisions regarding the specific cavity risks associated with each type of orthodontic appliance.

Gender: All

Ages: 13 Years - 45 Years

Updated: 2026-04-30

White Spot Lesions
Proximal Caries
Oral Hygiene in Orthodontic Patients
+1
NOT YET RECRUITING

NCT07171229

Evaluation of Cytokines Level as an Indicator of Pulp Inflammation and Its Relation to the Success Rates of Pulpotomy in Primary Molars Affected With Proximal Versus Occlusal Decay

pulpotomy will be done I primary molars with occlusal or proximal decay and level of cytokines will be measured as an indicator for pulp inflammation levels

Gender: All

Ages: 4 Years - 9 Years

Updated: 2025-09-12

Pulpitis - Reversible
Occlusal Caries
Proximal Caries
ACTIVE NOT RECRUITING

NCT06803537

Three-Year Clinical Performance of Fiber-reinforced Versus Indirect Resin Composite Posterior Restorations

This study aimed to perform a comparison between the clinical performance of short fiber-reinforced composite and indirect lab composite restorations in posterior dentition.

Gender: All

Ages: 20 Years - 35 Years

Updated: 2025-05-11

1 state

Occlusal Caries
Proximal Caries
ACTIVE NOT RECRUITING

NCT06724939

Clinical Evaluation of Self-Adhesive Bulk-Fil Hybrid Composite in Primary Molars

This study will evaluate the clinical performance of self-adhesive bulk-fill composite resin in the restoration of occlusal and occluso-proximal lesions in primary molars with hypothesis that there is no difference in the clinical performance of self-adhesive bulk-fill composite and traditional bulk-fill composite with adhesive over one year observation period

Gender: All

Ages: 4 Years - 6 Years

Updated: 2024-12-09

Occlual Caries
Proximal Caries
NOT YET RECRUITING

NCT06606379

Impact of Different Separation Methods on Proximal Contact Tightness and Contour of Compound Class ii

The aim of this study is to evaluate the interdental separation of various separation systems and their impact on the proximal contact tightness and contour in compound class II nanohybrid resin composite restorations.

Gender: All

Ages: 25 Years - 40 Years

Updated: 2024-09-23

Proximal Caries