Clinical Research Directory

Digital Psychoeducational Intervention for Young Adults With Fertility Related Distress Following Cancer Diagnosis

The goal of this randomized controlled trial is to evaluate the effectiveness of a digital psychoeducational intervention for young adults experiencing fertility-related distress following a cancer diagnosis. It will also assess how the intervention supports the development of effective coping strategies and social support networks. The main questions it aims to answer are: Does the digital psychoeducational intervention reduce anxiety and depression severity compared with usual care? Does the digital psychoeducational intervention increase patients' self-efficacy, social support, and coping compared with usual care? Does the digital psychoeducational intervention increase patients' quality of life compared with usual care? Researchers will compare the digital psychoeducational intervention to usual care (standard treatment) to see if the intervention effectively manages psychological problems and improves quality of life. Participants will:Be randomly assigned to either the experimental group or the control group. Attend an initial face-to-face introductory session, followed by four digital psychoeducational modules delivered via a mobile phone application (if assigned to the experimental group). Engage with module content including an e-booklet, video, and quizzes, with a new module opening every two days. Receive standard treatment from healthcare providers, and later receive the psychoeducational materials at the end of the data collection period (if assigned to the control group). Complete a series of validated questionnaires measuring depression, anxiety, coping, self-efficacy, social support, and quality of life at four different time points throughout the study.

Examining the Effect of a Group-Based Stress Management Course on Empowering the Mental Health of Medical Faculty Students and Resident Physicians: A Randomized Controlled Study

Physicians and medical students have higher rates of depression, anxiety, burnout, and suicide risk than the general population, and this disparity often begins early, even during medical school. Despite substantial distress, help-seeking is frequently limited due to stigma concerns, career fears, and time constraints, which may allow mental health problems to progress unnoticed and become chronic. Preventive interventions during medical education may reduce current distress and help avert more severe disorders later in professional life. Group-based psychoeducation is a cost-effective approach with advantages such as scalability, peer support, and learning benefits without requiring personal disclosure. The WHO Self-Help Plus (SH+) program is an ACT-informed, easily deliverable group stress management course, and randomized controlled trials across settings suggest SH+ can reduce psychological distress and depressive symptoms while improving coping skills and resilience. In Türkiye, evidence on group-based interventions for medical students and resident physicians remains limited and focuses mainly on documenting symptom levels rather than testing interventions; therefore, this study aims to evaluate a group-based stress management course and examine the feasibility and cultural adaptation of SH+-like programs in Turkish medical education.