Clinical Research Directory

Combined tDCS and Pneumatic Compression for Recovery After a 10K Run

This study will examine how two recovery methods-pneumatic compression (PC) applied to the legs and transcranial direct current stimulation (tDCS) applied to the head-help athletes recover after a 10-kilometer (10K) run. It also aims to find out which methods may help master athletes recover faster, maintain performance, and reduce the risk of injury. Men aged 40-55 who are trained long-distance runners can participate, provided they do not have medical conditions that prevent safe exercise or use of the recovery methods. Participants will run 10K and then receive one of the following interventions in a randomized order: tDCS, PC, tDCS + PC, or no intervention (control). Each participant will experience all conditions, with a one-week break between sessions. Measurements will be taken before the run, immediately after, and after the intervention, including heart rate variability, cognitive tests (Stroop Test), vertical jump, and maximal voluntary muscle contraction, during which muscle activity will be recorded using electromyography (EMG). Data will be analyzed to compare how each intervention affects recovery, including physical performance, cognitive function, and psychological state. The study will show which methods help master runners recover faster and more effectively, provide practical strategies to improve performance and reduce injury risk, and offer information on the separate and combined effects of tDCS and PC on recovery, which could help design age-specific recovery strategies for endurance athletes.

Effects of Blood Flow Restriction on Post-Exercise Recovery in Amateur Runners

Street running has become an increasingly popular sport. As a result, effective recovery strategies after exercise are essential. In this context, two techniques stand out: one already validated, active recovery (AR), and another with potential, blood flow restriction (BFR). This study aims to investigate whether using both techniques simultaneously can benefit practitioners and improve outcomes compared to complete rest.

A Randomized, Single-blind Trial of LI-TMS and AVS for Stoke Recovery in Healthy Participants (Phase 1).

This randomized, controlled, single-blind clinical pilot study investigates the therapeutic potential of low-intensity repetitive transcranial magnetic stimulation (LI-TMS) and audio-visual stimulation (AVS) and newly offered interventional protocols in healthy participants for further research on stroke rehabilitation and therapeutic effects. The goal of this clinical trial is to learn if the intervention can be used in the future treatment of patients recovering after stroke. It will also learn about the safety of low-intensity repetitive transcranial magnetic stimulation and audio-visual stimulation. The main questions it aims to answer are: Does intervention with LI-TMS and AVS influence the parameter Work Efficiency (WE) of the participant? Does intervention with LI-TMS and AVS influence the parameter Warming-up work indicator (WU) of the participant? Does intervention with LI-TMS and AVS influence the parameter Psychological Stability (PS) of the participant? Does intervention with LI-TMS and AVS influence the parameter Perceptual Accuracy (Tv) of the participant? Does intervention with LI-TMS and AVS affect changes in the participants electroencephalogram parameters? The researchers will compare the results of LI-TMS and AVS intervention to a control group that received no intervention but only underwent an examination to evaluate the effects of the interventions. Participants will: Receive interventions from LI-TMS and AVS every day for 2 weeks with a weekend break on Saturday and Sunday. Attend the clinic 3 times during the trial and undergo testing and screening. The first clinic visit is before the intervention course. The second clinic visit will be the day immediately following the end of the two-week intervention course. The third visit will be two weeks after the second visit.