Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

3 clinical studies listed.

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Refractory Myelodysplastic Syndromes

Tundra lists 3 Refractory Myelodysplastic Syndromes clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT06846606

Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS

This Phase 1, multicenter, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of AUTX-703 administered orally in subjects with advanced hematologic malignancies.

Gender: All

Ages: 18 Years - Any

Updated: 2026-03-03

8 states

Relapsed Acute Myeloid Leukemia (AML)
Refractory Acute Myeloid Leukemia (AML)
Relapsed/Refractory AML
+3
ACTIVE NOT RECRUITING

NCT04891757

FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies

This Phase 1, multicenter, open-label, dose escalation study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of FHD-286 administered orally as monotherapy or combination therapy, in subjects with advanced hematologic malignancies.

Gender: All

Ages: 16 Years - Any

Updated: 2025-07-10

5 states

Advanced Hematologic Malignancy
Relapsed Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
+4
ACTIVE NOT RECRUITING

NCT04623944

NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS

This is a single-arm, open-label, multi-center, Phase 1 study to determine safety and tolerability of an experimental therapy called NKX101 (allogeneic CAR NK cells targeting NKG2D ligands) in patients with relapsed/refractory AML or intermediate, high and very high risk relapsed/refractory MDS.

Gender: All

Ages: 18 Years - Any

Updated: 2024-12-27

7 states

Relapsed/Refractory AML
AML, Adult
MDS
+1