Clinical Research Directory

Optimizing and Advancing SBIRT in Schools

The goal of this clinical trial is to establish whether brief interventions for alcohol use can be delivered in schools for both indicated prevention and selected prevention, determine if an expanded workforce is an effective model for screening, brief intervention, and referral to treatment (SBIRT) delivery in schools, and explore whether brief intervention effectiveness is comparable in minoritized versus non-minoritized adolescents. Participants will be students at high schools across Massachusetts. High schools will be randomized to one of four intervention groups. Participants will complete a baseline survey prior to their school-wide screening for SBIRT, and then will complete four follow-up surveys over two years.

The Effect of Education Given to International University Students in Line With the Health Belief Model on Health Perception and Risky Behaviors

The World Health Organization defines health as a state of complete physical, mental, and social well-being. Health is a process in which individuals adapt to environmental changes, and this process is influenced by beliefs, experiences, and health behaviors. Health perception is a combination of an individual's thoughts about their own health and is a significant indicator of both physical and mental well-being. University students enter a new phase of life that can affect their health perceptions, during which they may experience health problems associated with factors such as stress, physical activity, and nutrition. International students, in particular, may encounter additional challenges during the cultural adaptation process and may engage in risky behaviors that affect their health behaviors.The Health Belief Model (HBM) is a framework used to understand and modify individuals' health behaviors. This study examines the effectiveness of an HBM-based educational intervention in evaluating international students' health perceptions and risky behaviors. While the literature supports the effectiveness of HBM-based education in reducing risky behaviors, there is a lack of randomized controlled trials conducted specifically with international students.This study, to be conducted with international students at Sakarya University, aims to improve students' health perceptions and reduce risky behaviors. The research is designed as a randomized controlled trial with pre-test/post-test, single-blind, experimental and control groups. It is expected that the HBM-based educational intervention delivered to the experimental group will enhance international university students' health perceptions and reduce their likelihood of engaging in risky behaviors.Data collection tools include the "Health Perception Scale" and the "Risky Behaviors Scale - University Form". Data obtained in the study will be analyzed using the SPSS (Statistical Package for the Social Sciences) for Windows 22.0 software.

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use. The main questions it aims to answer are: 1. How alcohol use impacts the PrEP continuum and to understand how early intervention and treatment approach affects alcohol use and PrEP adherence. 2. Investigate the effectiveness of the SBIRT intervention in preventing hazardous alcohol use and its impact on gut dysbiosis in PrEP users. 3. To determine alterations in the gut microbiome (dysbiosis), intestinal homeostasis, systemic inflammation, and markers of liver disease associated with hazardous alcohol use among PrEP users.

A Qualitative Mixed Methods Realist Evaluation of Safety Planning

Safety Planning is a recovery-orientated approach to risk management within mental health context. This study wants to answer the question 'how, why, for whom and it what circumstances does safety planning work? It will do this by carrying out a realist evaluation to identify programme theories by conducting a three phase study, reviewing materials of a Safety Planning training course, interviewing service users, carers and mental health professionals who have attended the training course, and/or use safety planning tools and techniques, adopting theory from existing literature and adding evaluator's insider knowledge. This data will be used to describe programme theory of safety planning that can be applied across diverse mental health settings, including NHS inpatient and community, and is designed to be adopted across different contexts. It will use a realist methodology to understand how safety planning works to develop the skills needed to manage risks associated with mental health difficulties in ways which increase an individual's quality of life.