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Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

5 clinical studies listed.

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Root Canal Therapy

Tundra lists 5 Root Canal Therapy clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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COMPLETED

NCT07808489

MB2 Canals in Pediatric Maxillary First Molars

This study examined how often an additional root canal, known as the second mesiobuccal canal (MB2), could be found in the upper first permanent molars of children aged 10-15 years. During root canal treatment, an endodontist followed a step-by-step approach using a standard clinical examination, magnifying loupes, a dental microscope, and, when clinically necessary, three-dimensional dental imaging. The study evaluated how much each step contributed to locating and confirming the canal.

Gender: All

Ages: 10 Years - 15 Years

Updated: 2026-09-08

1 state

Root Canal Therapy
COMPLETED

NCT07304869

Treatment Durations for Endodontic Procedures

The aim of this observational study is to compare the treatment durations of different stages of routine root canal therapy performed on maxillary molar teeth using direct vision, magnification loupes, and a dental operating microscope. The primary question the study seeks to answer is whether there is a significant difference in the duration of endodontic procedures performed under different magnification techniques. Patients indicated for root canal treatment in their maxillary first molar teeth will receive standard root canal therapy in accordance with routine clinical protocols. The duration of each procedural step will be recorded and subsequently compared among the three magnification methods.

Gender: All

Ages: 12 Years - Any

Updated: 2026-08-24

Root Canal Therapy
COMPLETED

NCT07413276

Prospective Evaluation of Clinical Endodontic Performance Assessment Methods

This prospective cohort study evaluates dental students' self-assessment of clinical endodontic performance and compares it with independent evaluations conducted in a dental education clinical setting. Endodontic treatments are performed by undergraduate dental students using two distinct rotary file systems selected according to routine clinical practice. Students' self-assessments are prospectively collected using a structured questionnaire and compared with evaluations performed by two experienced evaluators with access to clinical and radiographic information, considered the reference standard, as well as by two different experienced evaluators using radiographic information only. Secondary analyses examine whether assessment outcomes differ according to the rotary file system used. The null hypothesis is that there is no difference between dental students' self-assessments and reference standard evaluations of endodontic treatment quality, and that assessment outcomes do not differ according to the rotary file system used.

Gender: All

Ages: 18 Years - Any

Updated: 2026-06-02

1 state

Root Canal Therapy
NOT YET RECRUITING

NCT07477171

Mineral Trioxide Aggregate (MTA) vs Gutta-Percha for Non-Surgical Endodontic Retreatment in Teeth With Apical Lesions

The main objective of this study is to compare the healing rate of periapical lesions after non-surgical endodontic retreatment in teeth obturated with gutta-percha versus those obturated with mineral trioxide aggregate (MTA), with a 12-month follow-up. Secondary objectives include evaluating differences between groups in healing time, postoperative pain, and tooth discoloration.

Gender: All

Ages: 18 Years - Any

Updated: 2026-03-23

1 state

Periapical Diseases
Root Canal Therapy
Mineral Trioxide Aggregate (MTA)
NOT YET RECRUITING

NCT06972433

Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatment in Patients Visiting Scd, Swat.

This randomized controlled trial aims to compare the incidence of endodontic flare-ups in patients undergoing single-visit versus multiple-visit root canal treatment (RCT) at Saidu College of Dentistry, Swat. The study will recruit 344 patients aged above 10 and below 60 years, with permanent first molars indicated for RCT and meeting specific clinical and radiographic criteria. Participants will be randomly allocated into two groups: one receiving single-visit RCT and the other receiving multiple-visit RCT. Pain and flare-up incidence will be evaluated using the Visual Analog Scale (VAS) and swelling grading criteria at 6, 24, and 48 hours post-treatment. The primary outcome is the frequency of endodontic flare-ups requiring additional intervention. The study also examines the role of occlusal reduction in managing postoperative discomfort. Data will be analyzed using SPSS v23 with chi-square and Fisher's exact tests to compare outcomes. The findings aim to inform evidence-based protocols for endodontic treatment in the local population.

Gender: All

Ages: 10 Years - 60 Years

Updated: 2025-05-15

Postoperative Complication
Root Canal Therapy
Pulpitis - Irreversible