Clinical Research Directory

Effect of Sciatic Nerve Mobilization on Lower Extremity Pain Perception

This randomized controlled study aims to investigate the effect of sciatic nerve mobilization on pain perception in lower extremity peripheral nerves, specifically the tibial and common peroneal nerves. The study will be conducted in university students at Fenerbahçe University. Participants will be randomly assigned to either an intervention group or a control group. Pressure pain threshold (PPT) will be measured using a pressure algometer at standardized anatomical points over the tibial and common peroneal nerves before and after the intervention period. Demographic and clinical information, including age, sex, height, weight, dominant lower extremity, physical activity level, history of lower extremity injury or surgery, neurological or systemic disease, and regular medication use, will also be recorded. Participants in the intervention group will receive a standardized sciatic nerve mobilization protocol consisting of sliding-type neurodynamic mobilization performed in the supine position, including components of hip flexion, knee extension, and ankle dorsiflexion/plantarflexion in a rhythmic sequence. No intervention will be applied to the control group. The primary purpose of the study is to determine whether sciatic nerve mobilization changes pressure pain threshold values in the tibial and common peroneal nerves compared with no intervention.

Evaluation of Local Anesthetic Diffusion to the Sciatic Nerve During Adductor Canal Block

Adductor canal block is an effective analgesic technique for major knee surgery. However, the saphenous nerve block is not sufficient to explain this block's efficiency. It has been shown that adductor canal block can spread to the tibial and fibular nerves through the adductor hiatus. However, this diffusion's frequency has never been measured. The main objective of this study is to assess clinically the frequency of the spread of the adductor canal block to the fibular and tibial nerves.

Sciatic Nerve Stiffness Using Two-Sequences of Lower Limb Neurodynamic Testing: A Shear Wave Elastography Study

The purposes of the study are: 1. To measure differences in Sciatic nerve (SN) stiffness using shear-wave elastography (SWE) during two movement sequences of the lower limb neurodynamic test (LLNT) in low back pain with sciatica. 2. To measure differences in Sciatic nerve stiffness using shear-wave elastography during two movement sequences of the lower limb neurodynamic test in control group. 3. To compare difference in Sciatic nerve stiffness using shear-wave elastography during two movement sequences of the lower limb neurodynamic test between low back pain patients with sciatica and control group.