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Sodium-Glucose Transporter 2 Inhibitor

Tundra lists 1 Sodium-Glucose Transporter 2 Inhibitor clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT05590143

proMoting Effective Renoprotection in Cardiac sURgery Patients by Inhibition of SGLT-2

Multi-centre, triple-blinded (patients, physicians, investigators), parallel-group, balanced (1:1), stratified (sex, type 2 diabetes mellitus), randomized, controlled (placebo), phase IV clinical trial to investigate the potential of preoperative initiation (from day 1 before surgery) and perioperative continuation (until day 2 after surgery) of the SGLT2 inhibitor dapagliflozin 10 mg once daily to prevent AKI according to the KDIGO criteria (an increase in serum creatinine by 0.3 mg/dl (26.5 mmol/l) within 48 hours; or an increase in serum creatinine to 1.5 times baseline, within 7 days; or a urine output \<0.5 ml/kg/h for \>6 hours) in adult (\>18 years old) patients undergoing cardiopulmonary bypass surgery.

Gender: All

Ages: 18 Years - Any

Updated: 2025-05-18

Acute Kidney Injury

Cardiac Surgery

Sodium-Glucose Transporter 2 Inhibitor