Clinical Research Directory

Effectiveness of Enhanced Dialectical Behavior Therapy Skills Training Group for Borderline Personality Disorder

Dialectical Behavior Therapy (DBT) holds the strongest empirical support for the treatment of Borderline Personality Disorder (BPD). However, in Chile-as in much of Latin America-the availability of DBT falls significantly short of meeting patient demand. Despite its demonstrated efficacy, the duration of DBT and its multicomponent structure pose challenges for implementation and dissemination, particularly within public healthcare settings. This study aims to compare the clinical effectiveness of a 12-week DBT skills training group (12w-DBT-ST) with a quasi-standard 6-month DBT program (24w-DBT) and treatment as usual (TAU) for individuals with BPD in routine public mental health services. The primary hypothesis is that 12w-DBT-ST will be equivalent to the quasi-standard 24w-DBT and superior to TAU in reducing suicidal and self-harming behaviors.

Implementation of a Suicide Prevention Gatekeeper Program in the University Setting

The goal of this clinical trial is to assess the effectiveness of a suicide prevention training program (Gatekeepers) tailored to university students in Spain. The main questions it aims to answer are: * Does the training program improve suicide-related knowledge, attitudes, perceived behavioral control, and gatekeeper behaviors among students? * Are there differences in training outcomes by gender, and how do they affect program engagement and effectiveness? Researchers will compare a Immediate Intervention Group (GTK-IG), which will receive the full training immediately, with a 2) the Delayed Intervention Group (GTK-DG), which will be a waitlist control during the first phase of the study, to evaluate the program's short- and medium-term impact, using both in-person and online formats. which will be a waitlist control during the first phase of the study. Participants will: * Be randomly assigned to the intervention or control group, choosing between in-person or online training * Complete online surveys at three timepoints: before the program (T0), immediately after (T1), 2-3 months later (T2), and 9-12 months follow-up (T3). * Attend two 3-hour training sessions covering key suicide prevention competencies * Participate in a follow-up session with focus group discussion to qualitatively assess retention and use of learned skills * Complete validated questionnaires on suicide prevention literacy, attitudes, stigma, and self-reported gatekeeper behaviors This trial includes validation of the Spanish versions of the WISE (Willingness to Intervene Against Suicide Enhanced Questionnaire) and ACT as Gatekeeper measures. The study is registered at ClinicalTrials.gov and follows CONSORT and SPIRIT guidelines. Ethical approval was granted by the Human Research Ethics Committee at the University of Valencia.