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Clinical Research Directory

Browse clinical research sites, groups, and studies.

9 clinical studies listed.

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Tooth Decay

Tundra lists 9 Tooth Decay clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ENROLLING BY INVITATION

NCT07519382

Comparing the Clinical SUccess of Two Different CAD/CAM Full Cuspal Coverage Onlays

This is a single-center, ten-year, randomized controlled, split-mouth clinical trial. A total of 164 adult patients requiring full-cuspal coverage onlays will be enrolled. Each participant will receive one milled and one 3-D printed restoration, randomly assigned.

Gender: All

Ages: 18 Years - Any

Updated: 2026-04-09

1 state

Tooth Decay
NOT YET RECRUITING

NCT07261137

Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations

This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a procedure called direct pulp capping (DPC) if there is exposed pulp. Dental pulp is the part of the tooth that contains the nerves, blood vessels, and cells that keep your tooth healthy. This study will focus specifically on the liner/base application. In this study, the Solventum study product will be compared to a similar, commercially available product made by Solventum called 3M™ Vitrebond™ Plus Light Cure Glass Ionomer Liner/Base (Vitrebond Plus for short). The study will include participants who are at least 7 years old who have at least one tooth with moderate or advanced caries (tooth decay). The entire duration of the study is anticipated to be 2 years from when the first subject begins the study until the last subject completes the study. The duration of each study subject's participation will be up to 1 year consisting of an initial tooth restoration visit at baseline, a subject self-reported post-operative sensitivity assessment at 1 week reported by phone call, and in-person follow-up assessments at 1 month, 6 months, and 1 year post-restoration to confirm safety and effectiveness. The study will be partially blinded, which means that the participant and the dentist doing the assessments won't know which liner/base product is used on their tooth.

Gender: All

Ages: 7 Years - 89 Years

Updated: 2025-12-03

1 state

Caries, Dental
Tooth Decay
Dental Decay
+1
NOT YET RECRUITING

NCT07186673

Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children

The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to evaluate their effects on occlusal relationships, crown adaptation, and patient satisfaction. Study Outcomes The primary outcome of this study was to evaluate the clinical and radiographic success of stainless steel crowns placed on permanent first molars using the Hall Technique in comparison to the conventional crown placement method. The secondary outcomes included assessment of the marginal fit and adaptation of preformed crowns using both techniques, analysis of changes in occlusal relationships-specifically the vertical dimension of occlusion and overbite-and evaluation of patient satisfaction. Patient satisfaction was measured using a five-point Likert scale at multiple time points: immediately post-treatment, and at one, three, and six months.

Gender: All

Ages: 8 Years - 15 Years

Updated: 2025-11-28

Permanent Molars
Dental Caries
Tooth Decay
+1
NOT YET RECRUITING

NCT07231237

Clinical Study Evaluating Solventum™ Vitrebond™ Pulp Protect Liner/Base for Direct Capping of Pulpal Exposure

This research study is looking at the safety and effectiveness of Solventum™ Vitrebond™ Pulp Protect Liner/Base for direct pulp capping (DPC) on permanent teeth that have pulp exposure due either to deep cavities, trauma, or other accidental causes. Dental pulp is the part of the tooth that contains the nerves, blood vessels, and cells that keep teeth healthy. The DPC procedure is done by dentists to help preserve tooth health if there is pulp exposure during the tooth restoration or due to trauma. Participants must have at least one permanent tooth with pulp exposure that needs DPC to be eligible for the study.

Gender: All

Ages: 7 Years - 89 Years

Updated: 2025-11-17

1 state

Dental Caries
Pulp Exposure, Dental
Tooth Decay
+1
RECRUITING

NCT06286501

Targeting of Preventive Treatment for Adolescents at Risk of Oral Diseases

The aim of the study is to identify adolescent patients that are at risk of developing oral diseases, and to assess if targeted preventive oral treatment with antibacterial dual-light therapy as an adjunctive treatment method can have a positive impact in preventing oral diseases from emerging.

Gender: All

Ages: 14 Years - 16 Years

Updated: 2025-08-06

1 state

Dental Caries in Children
Dental Plaque
Tooth Decay
+1
NOT YET RECRUITING

NCT05792215

KAP of Dental Practitioners Regarding CRA

The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.

Gender: All

Updated: 2024-08-02

Caries,Dental
Tooth Decay
Tooth Diseases
RECRUITING

NCT06463574

Effect of Aging on Micro-tensile Bond Strength and Color Stability of Self-adhesive Resin Composite

The objective of this study is to evaluate the micro-tensile bond strength of a newly self-adhesive resinous restorative material to dentin with and without application of universal bonding system (in-vitro) and to examine it's clinical performance by evaluation of it's color stability and marginal discoloration through a randomized clinical trial (in-vivo).

Gender: All

Ages: 25 Years - 45 Years

Updated: 2024-06-18

Tooth Decay
NOT YET RECRUITING

NCT06447324

Clinical and Radiographic Evaluation of Two Matrix Systems for Restoration of Class II Cavities in Primary Molars

this study aims to evaluate and compare the clinical and radiographical efficacy, operator ease, satisfaction and patient comfort in restoring class II cavities in primary molars using Fender Mate system with T-band system.

Gender: All

Ages: 4 Years - 9 Years

Updated: 2024-06-10

Tooth Decay
Tooth Restoration
NOT YET RECRUITING

NCT06195449

Clinical and Radiographic Evaluation of Alkasite Restorative Material Versus Glass Ionomer Cement

To evaluate the clinical and radiographic performance of Alkasite restorative material versus glass ionomer in restoration of primary molars.

Gender: All

Ages: 5 Years - 7 Years

Updated: 2024-05-14

Tooth Decay