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Unresectable Lung Non-Squamous Non-Small Cell Carcinoma

Tundra lists 1 Unresectable Lung Non-Squamous Non-Small Cell Carcinoma clinical trial. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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ACTIVE NOT RECRUITING

NCT03965689

Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy

This phase II trial studies how well MLN4924 (pevonedistat), carboplatin, and paclitaxel work in treating patients with stage IIIB or IV non-small cell lung cancer. Pevonedistat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as carboplatin and paclitaxel, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pevonedistat together with carboplatin and paclitaxel may work better in treating patients with non-small cell lung cancer when compared with other standard chemotherapy drugs.

Gender: All

Ages: 18 Years - Any

Updated: 2026-04-09

6 states

Metastatic Lung Non-Small Cell Squamous Carcinoma

Metastatic Lung Non-Squamous Non-Small Cell Carcinoma

Stage IIIB Lung Cancer AJCC v8