Clinical Research Directory

The Validity and Reliability of an Improved Paper Grasping Test for Parkinson's Disease

The study will include volunteer patients diagnosed with Parkinson's disease who applied to the Neurology Outpatient Clinic at SANKO University Sani Konukoğlu Application and Research Hospital. Patients who meet the inclusion criteria will be evaluated by Dr. Hakan Polat and Physiotherapist Fatma Yılmaz in the application laboratory of the Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, SANKO University. The assessment form prepared by the researchers will be completed face-to-face with the patients. First, demographic information and disease-related data (duration since Parkinson's diagnosis, disease stage, affected side, etc.) will be recorded. The Mini-BESTest will be used to evaluate balance and gait. The muscle strength of the ankle plantar flexor and dorsiflexor muscles will be assessed using a manual muscle testing device, and quality of life will be measured with the Parkinson's Disease Questionnaire-39 (PDQ-39). Since fall problems in patients may be related to balance impairments, lower limb muscle weakness, and reduced quality of life, these parameters will also be evaluated. Therefore, in this study, while examining the validity and reliability of the modified paper grip test in individuals with Parkinson's disease, its correlation with these parameters will also be investigated. Before administering the tests, participants will receive a practical explanation of how the tests are performed and will be allowed to rest prior to assessment. The tests will be administered in the following order: first, the paper grip test by Dr. Hakan Polat, followed by the Mini-BESTest, assessment of ankle plantar and dorsiflexor muscle strength, and evaluation of quality of life. One week after the initial assessment, only the paper grip test will be re-administered by Physiotherapist Fatma Yılmaz in the same environment. This approach will minimize the effect of environmental factors on the patients' performance.

Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial

Objective: This study aimed to compare the efficacy and safety of oliceridine versus morphine and sufentanil for postoperative analgesia following elective lumbar spine surgery. Methods: In this randomized, controlled trial, 90 patients scheduled for lumbar spine surgery were allocated in a 1:1:1 ratio to receive postoperative intravenous patient-controlled analgesia (PCIA) with either oliceridine (Group O，1.5mg oliceridine for loading dose， 0.5mg/kg oliceridine for PICA), morphine (Group M，4mg morphine for loading dose，1.5mg/kg morphine for PICA), or sufentanil (Group S，4ug sufentanil for loading dose，1.5ug/kg sufentanil for PICA). The primary outcome was the movement Visual Analogue Scale (VAS) score at 6 hours postoperatively. Secondary outcomes included resting and movement VAS scores, ramsay sation score at 0.5, 2, 6, 12, 24, and 48 hours postoperatively (excluding the motor VAS score at 6 hours postoperatively); number of PCIA demands and rescue analgesic requirements within 48 hours; hemodynamic parameters at 5, 10, 15, 30, and 60 minutes after administration of the initial loading dose. The incidence of adverse events within 48 hours postoperatively, such as nausea and vomiting, somnolence, respiratory depression, or pruritus.

The Validity of the Evaluation of Renal Artery Duplex in Critically Ill Acute Kidney Injury Patients

This study aims to assess the clinical relevance of renal artery duplex ultrasound in critically ill patients with acute kidney injury (AKI) in terms of the renal resistive index (RRI).

Craniocervical Dysfunction Index in Patients With Temporomandibular Joint Dysfunction

The aims of this study were to perform cultural adaptation of the Craniocervical Dysfunction Index in patients with Temporomandibular Joint Dysfunction, reliability and validity of the index Turkish speaking adults.

Turkish Version of Digital Eye Strain Questionnaire (DESQ)

The aims of this study were to perform cultural adaptation of the DESQ and provide information regarding the factor structure, reliability and validity of the instrument in Turkish speaking adults.