Clinical Research Directory

Inclusion Criteria: * Patient female or male aged between 18 and 65 * Patients with a haematological disease and ran for a first-line chemotherapy including anthracycline * Patients with a predict cardiovascular score to 10 years below 20% or if higher, with a stress echocardiography using dobutamine, negative, for less than six months. * Patient or affiliate receiving social security * Patient informed consent and having oral and written Exclusion Criteria: * A history of chemotherapy or radiotherapy of the left hemithorax * Significant coronary artery disease: a history of angioplasty, stent, CABG, predict cardiovascular score to 10 years over 20% of stress echocardiography and dobutamine positive (three positive segments) * Left ventricular hypertrophy (diastolic septum ≥ 10 mm and diastolic posterior wall ≥ 10 mm) * One or more significant valvulopathy: Rao, RM medium or tight, IM, IT and CAI ≥ grade 2 * Secondary or primary cardiomyopathy (LVEF ≤ 50%) * Pregnant or lactating