Clinical Research Directory

Inclusion Criteria FHP: * Exposure to cannabis at least once in their lifetime * Medically and psychiatrically healthy based on screening * Having one relative with a confirmed psychotic disorder Exclusion Criteria FHP: * Current or lifetime major DSM-IV Axis I disorder * Current or lifetime treatment (at least 6 months) with psychotropic medications for major psychiatric or neurological illness * Major or unstable medical illness that might impact safety of the subject in the study * Cannabis naive * IQ less than 85 * Less than a high school diploma or its educational equivalent * Pregnancy or lactation * Major current or recent (\<6 weeks) psychosocial stressors. Inclusion Criteria FHN : * Exposure to cannabis at least once in their lifetime * Medically and psychiatrically healthy based on screening Exclusion Criteria FHN: * Having a family member with psychosis * Current or lifetime major DSM-IV Axis I disorder * Current or lifetime treatment (at least 6 months) with psychotropic medications for major psychiatric or neurological illness * Major or unstable medical illness that might impact safety of the subject in the study * Cannabis naive * IQ less than 85 * Less than a high school diploma or its educational equivalent * Pregnancy or lactation * Major current or recent (\<6 weeks) psychosocial stressors.