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COMPLETED
NCT03814304
NA

Personalized tDCS in Elderly Fallers Study

Sponsor: Hebrew SeniorLife

View on ClinicalTrials.gov

Summary

The objective of this study is to determine if a four-week, 20-session intervention of personalized transcranial direct current stimulation (tDCS), as compared to sham intervention, improves dual task standing and walking performance (Aim 1), as well as other physical (Aim 2) and cognitive (Aim 3) factors on the causal pathway to falls, in older adults who report two or more falls within the past year and fear of falling again in the future, yet who do not have any acute or over neurological or musculoskeletal condition. Primary endpoints will include the "dual task" costs to gait speed when walking and postural sway speed when standing, as induced by performing a serial subtraction cognitive task (i.e., \[(speeddual task - speedsingle task) / speedsingle task) X 100\] (Aim 1), the Short Physical Performance Battery (Aim 2), and the Trail Making Test (Part B minus Part A) (AIM 3). Secondary endpoints will include the dual task cost to serial subtraction performance, additional gait and balance outcomes derived from the dual task paradigm, the Timed Up-and-Go, fear of falling, habitual physical activity, and performance within a battery of neuropsychological tests focused on global cognitive function, attention, verbal fluency and memory.

Official title: Personalized Brain Activity Modulation to Improve Balance and Cognition in Elderly Fallers

Key Details

Gender

All

Age Range

60 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

118

Start Date

2019-07-08

Completion Date

2025-07-31

Last Updated

2026-06-16

Healthy Volunteers

No

Interventions

OTHER

Personalized tDCS

The participant will receive 20, 20-minute sessions of personalized tDCS on Monday-Friday, at approximately the same time of day, over four consecutive weeks.

OTHER

Active-Sham

The participant will receive 20, 20-minute sessions of active-sham stimulation on Monday-Friday, at approximately the same time of day, over four consecutive weeks.

Locations (1)

Hebrew Rehabilitation Center

Roslindale, Massachusetts, United States