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Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia
Sponsor: Montreal Heart Institute
Summary
This is an observational study of the occurrence of cardiac toxicity in patients with breast cancer,lymphoma or leukemia receiving chemotherapy including an anthracycline. Patients will be identified at the oncology clinic and will be included in the study if all eligible criteria are met. The study will involve retrospective and prospective evaluations. Safety will be assessed through reporting of serious adverse events (SAEs) related to study procedures.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
169
Start Date
2021-12-02
Completion Date
2027-09-30
Last Updated
2025-06-15
Healthy Volunteers
Not specified
Conditions
Interventions
Cardiac Imaging
Cardiac Imaging: echography, ECG, MRI Blood tests: Lipid profile, hs-CRP, metabolic markers, HDL functionality, pharmacogenetic testing (optional), hematocrit, pregnancy test
Data Collection
Collection of retrospective data
Locations (6)
Centre Hospitalier de l'université de Montréal (CHUM)
Montreal, Quebec, Canada
CIUSSS Ouest de l'ile de Montreal - St-Mary's Hospital
Montreal, Quebec, Canada
CIUSSS de l'Est-de-l'Île-de-Montréal - Hôpital Maisonneuve-Rosemont
Montreal, Quebec, Canada
CIUSSS du Centre-Ouest de l'Île de Montréal - Jewish General Hospital
Montreal, Quebec, Canada
Montreal Heart Institute
Montreal, Quebec, Canada
CISSSS de Lanaudière_Hôpital Pierre LeGardeur (referring site)
Terrebonne, Quebec (QC), Canada