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ACTIVE NOT RECRUITING
NCT04648371
NA

Community-based Cognitive Remediation and tDCS to Enhance Seniors' Function and Mental Health

Sponsor: Centre for Addiction and Mental Health

View on ClinicalTrials.gov

Summary

Focusing on seniors with mental health conditions who are living in the community, this initiative proposes to assess the acute and long-term effects of an 8-week course of daily (5 days/week) cognitive remediation (CR) training among 270 participants living in five LOFT senior housing units. The acute course of CR will be followed by monthly one-week boosters until the end of this 5-year study, totaling approximately 24-60 months of follow-up. This trial will also be used as a platform to explore the ability to use transcranial direct current stimulation (tDCS) to optimize response to CR by participant randomization to active versus sham tDCS. Our ultimate goal is to improve the lives of seniors experiencing mental illness and shape a future where they can live independently.

Key Details

Gender

All

Age Range

50 Years - Any

Study Type

INTERVENTIONAL

Enrollment

18

Start Date

2021-01-27

Completion Date

2026-05-22

Last Updated

2024-02-29

Healthy Volunteers

No

Interventions

OTHER

Cognitive Remediation and Transcranial Direct Current Stimulation

Cognitive Remediation (CR) is a well-established psychosocial group intervention that aims to improve neurocognitive abilities such as memory performance, executive functioning, processing speed, and attention. Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation method that can be safely administered to awake outpatients. It does not require general anesthesia or surgical implantation. It utilizes low intensity electrical current (e.g., 2 mA) either to increase cortical excitability with an anodal electrode or to suppress cortical excitability with a cathodal electrode.

Locations (1)

Centre for Addiction and Mental Health

Toronto, Ontario, Canada