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RECRUITING

NCT04953806

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

Chronic Obstructive Pulmonary Disease (COPD) is prevalent and debilitating chronic disease in Veterans. COPD is highly co-morbid with depression and anxiety conferring greater morbidity and mortality risk. Physical activity is a modifiable behavior that can improve COPD outcomes. However, to date, interventions targeting physical activity have not addressed the high comorbidity between COPD and depression and/or anxiety symptoms ("emotional distress") despite emotional distress predicting poorer response to physical activity interventions. This CDA-2 proposal will develop and test the acceptability and feasibility of an integrative physical activity and mental health intervention for Veterans with COPD, emotional distress, and low physical activity. The intervention will be delivered via VA Video Connect enabling access to care among Veterans with substantial barriers to hospital-based outpatient care.

Key Details

Gender

All

Age Range

40 Years - Any

Study Type

INTERVENTIONAL

Enrollment

Start Date

2021-11-02

Completion Date

2026-10-31

Last Updated

2025-06-24

Healthy Volunteers

Conditions

COPD Depression Anxiety

Interventions

BEHAVIORAL

Step-CBT

Participants will complete Step-CBT, an integrative 8-week physical activity and cognitive behavioral therapy (CBT) intervention, delivered by a licensed clinical psychologist. Sessions will take place once per week for 60 minutes using VA Video Connect. Each session will include core components 1) Reviewing physical activity goals, prescribing new step count goal, and problem-solving barriers and 2) The weekly CBT intervention module.

Inclusion Criteria: * Any gender-identified, greater than or equal to 40 years of age * Clinical diagnosis of COPD defined as the presence of emphysema on a CT scan and one piece of clinical evidence of COPD (defined as a ratio of FEV1 to forced vital capacity \< 0.70, \> 10 pack-year cigarette smoking history, overall assessment of COPD in their problem list or in Pulmonary/Primary Care notes, or on bronchodilators (specifically antimuscarinics such as Tiotropium or Ipratropium). If there is no evidence of emphysema, or no CT on scan in their medical chart, three pieces of clinical evidence of COPD will suffice for a clinical diagnosis of COPD. * Ability to communicate * Able to participate in in-person study appointment at the VA * English speaking * Competent to provide informed consent * Emotional distress. Clinically significant depression and/or anxiety defined as PHQ-8 \> 10 and/or Beck Anxiety Inventory \> 13 * Wireless Internet connection and Bluetooth capability * Participants with \> 90% accuracy of device Fitbit to manual step counts * Agreeable to audio record study session * Agreeable to wearing an ActiGraphy device and Fitbit and downloading the Fitbit app * Email user for VVC visits links * Either owns a smartphone or iPad compatible with the Fitbit app and enabled with Bluetooth or agreeable to using a study-issued iPad with Wi-Fi and Bluetooth capabilities * Medical clearance from healthcare provider to participate in a physical activity program Exclusion Criteria: * COPD exacerbation in the previous 1 month * Inability to ambulate * Regular use of a rollator, walker, or wheelchair for ambulation * Inability to complete questionnaires * Inability to collect at least 4 valid days of 7-day baseline step count data * Positive screening on the Mini-Cog defined as \< 3 indicating possible cognitive impairment or dementia or major neurocognitive disorder diagnosis in electronic medical chart or refusal to complete the assessment * Currently enrolled in another interventional study targeting exercise, physical activity, or mental health * Average baseline step counts of greater than or equal to 10,000 steps per week * Suicide flag in chart * Oxygen saturation after 6-Minute Walk Test documented to be \<85%

Locations (1)

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, United States