Clinical Research Directory
Browse clinical research sites, groups, and studies.
Using Nicotine to Reverse Age-related Auditory Processing Deficits
Sponsor: University of California, Irvine
Summary
The present study will evaluate the effects of both aging and nicotine on psychophysical tasks and electrophysiological measures. Nicotine will be administered to study participants in the form of gum that is available as an over-the-counter medication. The hypothesis is that nicotine will reverse the detrimental effects of aging on auditory processing. The proposed experiments will characterize the effects of nicotine and may eventually lead to improved treatments of hearing loss in a variety of patient populations and in healthy aging.
Official title: Using Nicotine to Reverse Age-related Auditory Processing Deficits: Human Psychophysics and Electrophysiology
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2022-02-01
Completion Date
2026-06-30
Last Updated
2026-03-27
Healthy Volunteers
Yes
Conditions
Interventions
Nicotine gum
Nicotine (6 mg) will be administered in the form of polacrilex gum that is available as an over-the-counter medication
Placebo gum
The placebo will also be a commercially available gum that resembles the nicotine gum in flavor, size, shape, color, and texture.
Locations (1)
Hearing and Speech Lab
Irvine, California, United States