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RECRUITING
NCT05950867
NA

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Sponsor: Universitair Ziekenhuis Brussel

View on ClinicalTrials.gov

Summary

To investigate to what extent chronic axonal length-dependent polyneuropathy (CAP) and/or small-fiber neuropathy (SFN) is part of early non-cardiac manifestations of wild-type TTR cardiac amyloidosis (wtTTR-CA). Consequently, explore whether this could ultimately lead to faster diagnosis and clinical outcome of wild-type TTR cardiac amyloidosis (wtTTR-CA).

Official title: Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause: a Prospective Monocentric Study (CAP-TTR)

Key Details

Gender

All

Age Range

60 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150

Start Date

2023-07-28

Completion Date

2026-06-01

Last Updated

2025-07-22

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

ECG + echocardiography

Electrocardiogram and echocardiography

OTHER

Answering questionnaires

Answering questionnaires about polyneuropathy symptoms (NTSS -6, COMPASS31, NIS, mPND) and also cardialogical symptoms (KCCQ-12).

Locations (1)

UZ Brussel

Jette, Belgium Capital City, Belgium