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Adipose Tissue Blood Flow in Aging Humans
Sponsor: Mayo Clinic
Summary
The goal of this basic science clinical trial is to understand whether adipose tissue blood flow changes between younger and older healthy adults. The main question\[s\] it aims to answer are: * Is basal and nutrient responsive adipose tissue blood flow (ATBF) different between younger and older adults * What molecular and systemic signatures related to adipose tissue blood flow are altered between these two groups. Participants will undergo measurements of adipose tissue blood flow using the xenon washout technique, undergo 2 abdominal subcutaneous adipose tissue biopsies, and drink a sugary drink.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
24
Start Date
2024-01-15
Completion Date
2028-12-30
Last Updated
2026-02-11
Healthy Volunteers
Yes
Interventions
75 gm oral glucose load
Consumption of 75 gm oral glucose load in order to test nutrient responsiveness
Locations (1)
Mayo Clinic Minnesota
Rochester, Minnesota, United States