Clinical Research Directory

Inclusion Criteria: * ≥25 years old and legally competent * Palliative oncological therapy * ECOG status 1, 2 or 3, incapacitated for work * ESAS TSDS \> or equals 16 * Nutritional Risk Screening \> or equals 3 * Pain numerical rating scale \> or equals 4 * informed consent * for WOCBP: * Negative pregnancy test * Reliable contraception (Pearl Index \< 1%) Exclusion Criteria: * nausea \> or equals grade 3 (CTCAE) or vomiting \> or equals grade 2 (CTCAE) in the preceding week * Inability to understand and complete the questionnaires * Cannabis use in the last 6 weeks * Alcohol addiction * Pregnancy/lactation * Contraindications or intolerance to the study medication (esp. psychosis) * Simultaneous participation in other clinical studies (sumulataneous participation in non-interventional studies (i.e. biomarker-studies, registries) is allowed, if the study-aim does not interfere with measures of the second study) * Any other condition as judged by the investigator, e.g. non-compliance