Clinical Research Directory

Inclusion Criteria: * all phototypes * only one of the following pigmentary conditions on the face: epidermal or mixed, mild to moderate melasma; mild to moderate acne-induced PIHP; solar lentigo * female patient of childbearing potential must use one of the reliable methods of contraception and agree not to change it during the study * patient agreeing not to be exposed to ultraviolet radiation (UV), natural (sun) or artificial (tanning salon), during the study Exclusion Criteria: * female patient who gave birth less than 3 months prior to Day 0, who is pregnant, breast-feeding or who plans to become pregnant during the study * male patient with beard or facial hair, which would interfere with clinical evaluation or clinical procedure baseline) * patient with any inflammatory dermatosis of the face such as seborrheic dermatitis, rosacea etc. * severe melasma, dermal melasma * patient with facial pigmentary disorders other than those described in inclusion criteria * patient who has used topical depigmenting agents such as hydroquinone and derivatives, glycolic acid, kojic acid, retinoids and derivatives, azelaic acid, niacinamide within 1 month prior to Day 0/Baseline visit * patient who has used systemic treatments such as tranexamic acid and oral melatonin within 1 month prior to Day 0/Baseline visit; * patient who has used drugs inducing pigmentation such as tetracyclines, fluoroquinolones, antiepileptics within 1 month prior to Day 0/Baseline visit