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Clinical Research Directory

Browse clinical research sites, groups, and studies.

10 clinical studies listed.

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Hyperpigmentation

Tundra lists 10 Hyperpigmentation clinical trials. Each listing includes eligibility criteria, study locations, and direct links to research sites in the Tundra directory.

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NOT YET RECRUITING

NCT07429786

Evaluation of Efficacy and Tolerabilty of MelaB3 Serum in Combination of 35% Glycolic Acid Peeling Compared to 35% Glycolic Acid Peeling Alone in Various Hyperpigmentation Conditions

Randomized clinical trial to assess the effectiveness and tolerability of Mela B3 serum in combination with 35% glycolic acid peel vs. 35% glycolic acid peel for the treatment of various hyperpigmentation conditions (melasma, post-inflammatory hyperpigmentation and solar lentigo) and signs of aging in a population of participants from the Autonomous City of Buenos Aires, Argentina.

Gender: All

Ages: 30 Years - 70 Years

Updated: 2026-02-24

Hyperpigmentation
Melasma
Solar Lentigo
+1
ACTIVE NOT RECRUITING

NCT07162623

Clinical Study to Assess Safety, Efficacy and In-Use Tolerability of Oziva Bioactive Gluta Fizzy Effervescent Tablets on Subjects With Facial Dark Spots Such as Pimple Marks, Sunspots, Age Spots and Uneven Skin Tone

This is a randomized, double-blinded, single-centre, two-arms, placebo-controlled, prospective study to evaluate clinical safety, efficacy and in-use tolerability of Test Product i.e. Oziva Bioactive Gluta Fizzy Effervescent tablets in subjects with facial hyperpigmentation and dark spots.

Gender: All

Ages: 21 Years - 55 Years

Updated: 2026-01-30

1 state

Hyperpigmentation
NOT YET RECRUITING

NCT07324759

Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.

This is a randomized, double-blind, comparative, two-arm, prospective, interventional, multi-centre clinical study to evaluate the safety, efficacy, and in-use tolerability of test products, standardized saffron extract capsules, on skin rejuvenation and age-defying benefits in healthy adult male and female subjects.

Gender: All

Ages: 30 Years - 55 Years

Updated: 2026-01-07

Wrinkles
Fine Lines
Hyperpigmentation
+1
ENROLLING BY INVITATION

NCT07136766

An 18-week Study to Evaluate a Test Product With a Marketed Prescription Product

The purpose of this study is to assess the efficacy (ability to produce a desired or intended result) of a topical product (applied to the skin) to improve skin lightness, skin condition and appearance (hyperpigmentation \[dark spots\], brightness/radiance \[healthy vibrant appearance\], skin texture \[smoothness\]) on \] the face over a period of eighteen (18) weeks. The data collected may support the company in developing marketing claims for its product.

Gender: FEMALE

Ages: 18 Years - 75 Years

Updated: 2025-08-22

1 state

Hyperpigmentation
ACTIVE NOT RECRUITING

NCT07067515

Effectiveness of Omega-3 Poly Unsaturated Fatty Acids on The Treatment of Gingival Hyperpigmentation

This new study compares the effectiveness of scalpel surgery and omega-3 poly unsaturated fatty acid (PUF) injections in treating gingival hyperpigmentation.

Gender: All

Ages: 21 Years - 50 Years

Updated: 2025-07-16

Hyperpigmentation
Gingival Hyperpigmentaion
RECRUITING

NCT07067879

The Effectiveness of a Novel Lip Product Containing Caulerpa Lentillifera Extract for Reducing Lip Hyperpigmentation

The goal of this clinical trial is to evaluate the efficacy of the novel lip product containing Caulerpa lentillifera extract on the appearance and perception of dark lips in Thai adults aged 18 to 60 who report concerns about darkened lips. The main question it aims to answer is: Can the novel lip product containing C. lentillifera extract will significantly improve the appearance and perception of dark lips in Thai adults by reducing hyperpigmentation compared to baseline measurements? Participants will apply the lip product twice a day, in the morning after breakfast and before bedtime, and refrain from using other lip products throughout the clinical trial period (7 days). Researchers will compare the result to baseline measurements

Gender: All

Ages: 18 Years - 60 Years

Updated: 2025-07-16

Hyperpigmentation
RECRUITING

NCT05362929

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.

Gender: All

Ages: 18 Years - Any

Updated: 2025-05-22

1 state

Acne Scars - Mixed Atrophic and Hypertrophic
Hyperpigmentation
Laser-Induced Hyperpigmentation
RECRUITING

NCT06253468

Efficacy and Tolerability of Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins

The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to moderate melasma, or mild to moderate acne induced post-inflammatory hyperpigmentation, or solar lentigo.

Gender: All

Ages: 18 Years - Any

Updated: 2024-08-06

Hyperpigmentation
RECRUITING

NCT06268496

Efficacy and Tolerability of the Tested Formula After 3 Months in Treatment of Facial Hyperpigmentation of 3 Origins

The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to moderate melasma, or mild to moderate acne induced post-inflammatory hyperpigmentation, or solar lentigo.

Gender: All

Ages: 18 Years - Any

Updated: 2024-07-12

Hyperpigmentation
RECRUITING

NCT06349447

Pilot Study of LED for PIE and PIH

The aim of this study is to explore the effect of medical LEDs (830 nm and 590 nm) in the prevention and treatment of PIE and PIH.

Gender: All

Ages: 20 Years - 65 Years

Updated: 2024-04-05

Hyperpigmentation