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Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
Sponsor: Children's National Research Institute
Summary
There is a significant unmet need for optimized treatment in rhabdomyolysis. There are few prospective interventional studies on treatment for rhabdomyolysis, a condition which affects diverse and underrepresented populations at a higher rate. While steroids are often used off-label, a systematic study has not yet been initiated, and steroids have not been yet considered in as a consideration to standard care guidelines. The hypothesis is that patients who receive dexamethasone in addition to standard care versus placebo and standard care will have improvement in pain, length of hospital stay, and decrease in kidney complications.
Official title: A Clinical Trial to Assess Whether Dexamethasone Addition to Standard Protocols for Non-Traumatic Rhabdomyolysis of Unknown or Genetic Etiologies Improves Patient Outcomes
Key Details
Gender
All
Age Range
6 Months - 25 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-10-01
Completion Date
2026-12-31
Last Updated
2025-07-03
Healthy Volunteers
No
Conditions
Interventions
Dexamethasone
Steroid five day treatment
Placebo
Placebo control group
Locations (1)
Childrens National
Washington D.C., District of Columbia, United States