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RECRUITING
NCT06429982
PHASE1

Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols

Sponsor: Children's National Research Institute

View on ClinicalTrials.gov

Summary

There is a significant unmet need for optimized treatment in rhabdomyolysis. There are few prospective interventional studies on treatment for rhabdomyolysis, a condition which affects diverse and underrepresented populations at a higher rate. While steroids are often used off-label, a systematic study has not yet been initiated, and steroids have not been yet considered in as a consideration to standard care guidelines. The hypothesis is that patients who receive dexamethasone in addition to standard care versus placebo and standard care will have improvement in pain, length of hospital stay, and decrease in kidney complications.

Official title: A Clinical Trial to Assess Whether Dexamethasone Addition to Standard Protocols for Non-Traumatic Rhabdomyolysis of Unknown or Genetic Etiologies Improves Patient Outcomes

Key Details

Gender

All

Age Range

6 Months - 25 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2024-10-01

Completion Date

2026-12-31

Last Updated

2025-07-03

Healthy Volunteers

No

Conditions

Interventions

DRUG

Dexamethasone

Steroid five day treatment

DRUG

Placebo

Placebo control group

Locations (1)

Childrens National

Washington D.C., District of Columbia, United States