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Olive Leaf Extract, Meta-inflammation, Anxiety, and Excess Weight
Sponsor: University of Guadalajara
Summary
Excess Weight is accompanied by a process that produces a low-grade inflammation state, called meta-inflammation. Anxiety is also associated with inflammation. Inflammation is closely related to oxidative stress. Both processes help perpetuate each other. Olive Leaf Extract (OLE) is known for having anti-inflammatory and antioxidant effects; by this means, its anxiolytic effect has been proved in animal models. The purpose of this investigation is to evaluate the anti-inflammatory and anxiolytic effects associated with the supplementation of OLE at a daily dose of 750mg (20% oleuropein) for 3 months.
Official title: Olive Leaf Extract Effects on Meta-inflammation and Anxiety Symptoms in Women With Excess Weight
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2024-10-16
Completion Date
2026-01-31
Last Updated
2024-10-18
Healthy Volunteers
No
Conditions
Interventions
Olive Leaf Extract (OLE)
Daily dose of 750mg OLE consumed with water after breakfast without any modification of their dietary patterns for 90 days.
Placebo
100mg microcrystalline cellulose
Locations (1)
Universidad de Guadalajara
Guadalajara, Jalisco, Mexico